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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1071657Generated: November 3, 2026

1-(2-((5-Chloropyridin-3-yl)oxy)ethyl)piperazine → 1-[4-Cyano-4-(5-cyano-2-thienyl)-5-methylhexyl]-4-[2-(5-chloro-3-pyridyloxy)ethyl]piperazine

https://huagongshe.com/reaction/1071657

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-((5-Chloropyridin-3-yl)oxy)ethyl)piperazineHCID 22393711—
Reactant4-Cyano-4-(5-cyano-2-thienyl)-5-methylhexyl iodideHCID 22393730—
Product1-[4-Cyano-4-(5-cyano-2-thienyl)-5-methylhexyl]-4-[2-(5-chloro-3-pyridyloxy)ethyl]piperazineHCID 22393841—

Reaction Steps

The title compound was synthesized in accordance with Example 77 from 4-cyano-4-(5-cyano-2-thienyl)-5-methylhexyl iodide and 1-[2-(5-chloro-3-pyridyloxy)ethyl]piperazine. The physico-chemical data of the compound was as below.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06906072B1
Source datasetuspto-grants-2005_06
ORD IDord-9b0bed690d4745dba49c9b4aa8ef24ba
Source noteuspto-grants-2005_06