α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrile → HCID 22393800, compound

HRID 1071659Notes

Reaction equation

HRID 1071659 reaction equation
[C:1]([C:3]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6]I)#[N:2].[N:16]1[CH:21]=[CH:20][CH:19]=[C:18]([NH:22][CH:23]2[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]2)[CH:17]=1>>[C:1]([C:3]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6][N:26]1[CH2:27][CH2:28][CH:23]([NH:22][C:18]2[CH:17]=[N:16][CH:21]=[CH:20][CH:19]=2)[CH2:24][CH2:25]1)#[N:2]

Participants

3

Reactant 2

HCID 22393563α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrileHCID 22393771N-(piperidin-4-yl)pyridin-3-amine

Product 1

HCID 22393800HCID 22393800, compound

Procedure

The title compound was synthesized in accordance with Example 75 from 4-cyano-4-(2-thienyl)-5-methylhexyl iodide and 4-(3-pyridylamino)piperidine. The physico-chemical data of the compound was as below.

Sources & evidence

ORD record
ord-f354900623194e1a90ce453e47b4d6fd
Source dataset
uspto-grants-2005_06
Patent number
US06906072B1

Reaction notes

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