Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1071660Generated: November 3, 2026

α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrile → 1-[4-Cyano-4-(2-thienyl)-5-methylhexyl]-4-[2-(6-methoxymethyl-2-pyridyloxy)ethyl]-piperazine

https://huagongshe.com/reaction/1071660

Reaction equation

Participants

RoleNameHCIDCharge
Reactantα-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrileHCID 22393563—
Reactant1-(2-(6-Methoxymethyl-2-pyridyloxy)ethyl]piperazineHCID 22393690—
Product1-[4-Cyano-4-(2-thienyl)-5-methylhexyl]-4-[2-(6-methoxymethyl-2-pyridyloxy)ethyl]-piperazineHCID 22393647—

Reaction Steps

The titile compound was synthesized in accordance with Example 75 from 4-cyano-4-(2-thienyl)-5-methylhexyl iodide and 1-(2-(6-methoxymethyl-2-pyridyloxy)ethyl]piperazine. The physico-chemical data of the compound was as below.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06906072B1
Source datasetuspto-grants-2005_06
ORD IDord-ce1d8fe6879f46bcafa839ed7e57765d
Source noteuspto-grants-2005_06