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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1071663Generated: October 31, 2026

α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrile → 1-[4-Cyano-4-(2-thienyl)-5-methylhexyl]-4-[2-(6-fluoro-2-pyridyloxy)ethyl]piperazine

https://huagongshe.com/reaction/1071663

Reaction equation

Participants

RoleNameHCIDCharge
Reactantα-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrileHCID 22393563—
Reactant1-[2-(6-Fluoro-2-pyridyloxy)ethyl]piperazineHCID 22393668—
Product1-[4-Cyano-4-(2-thienyl)-5-methylhexyl]-4-[2-(6-fluoro-2-pyridyloxy)ethyl]piperazineHCID 22393802—

Reaction Steps

The title compound was synthesized in accordance with Example 75 from 4-cyano-4-(2-thienyl)-5-methylhexyl iodide and 1-[2-(6-fluoro-2-pyridyloxy)ethyl]piperazine. The physico-chemical data of the compound was as below.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06906072B1
Source datasetuspto-grants-2005_06
ORD IDord-7c09fc25d90b488691792c5cae8967d7
Source noteuspto-grants-2005_06