α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrile → HCID 22393712, compound

HRID 1071664Notes

Reaction equation

HRID 1071664 reaction equation
[C:1]([C:3]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6]I)#[N:2].[N:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[O:22][CH2:23][CH2:24][N:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1>>[C:1]([C:3]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6][N:28]1[CH2:29][CH2:30][N:25]([CH2:24][CH2:23][O:22][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][N:16]=2)[CH2:26][CH2:27]1)#[N:2]

Participants

3

Reactant 2

HCID 22393563α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrileHCID 22393716HCID 22393716, compound

Product 1

HCID 22393712HCID 22393712, compound

Procedure

The title compound was synthesized in accordance with Example 75 from 4-cyano-4-(2-thienyl)-5-methylhexyl iodide and 1-[2-(2-pyridyloxy)ethyl)piperazine. The physico-chemical data of the compound was as below.

Sources & evidence

ORD record
ord-a4344990ee824f6b8f615d20d10af07c
Source dataset
uspto-grants-2005_06
Patent number
US06906072B1

Reaction notes

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