α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrile → HCID 22393812, compound

HRID 1071665Notes

Reaction equation

HRID 1071665 reaction equation
[C:1]([C:3]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6]I)#[N:2].[CH3:16][C:17]1[N:22]=[C:21]([O:23][CH2:24][CH2:25][N:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[CH:20]=[CH:19][CH:18]=1>>[C:1]([C:3]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6][N:29]1[CH2:30][CH2:31][N:26]([CH2:25][CH2:24][O:23][C:21]2[CH:20]=[CH:19][CH:18]=[C:17]([CH3:16])[N:22]=2)[CH2:27][CH2:28]1)#[N:2]

Participants

3

Reactant 2

HCID 22393563α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrileHCID 223936851-[2-(6-Methyl-2-pyridyloxy)ethyl]piperazine

Product 1

HCID 22393812HCID 22393812, compound

Procedure

The title compound was synthesized in accordance with Example 75 from 4-cyano-4-(2-thienyl)-5-methylhexyl iodide and 1-[2-(6-methyl-2-pyridyloxy)ethyl]piperazine. The physico-chemical data of the compound was as below.

Sources & evidence

ORD record
ord-ebc34afb684944a79c0a16ebb65d952c
Source dataset
uspto-grants-2005_06
Patent number
US06906072B1

Reaction notes

Loading…