4-Cyano-4-(5-cyano-2-thienyl)-5-methylhexyl iodide → 1-[4-Cyano-4-(5-cyano-2-thienyl)-5-methylhexyl]-4-[2-(6-cyano-2-pyridyloxy)ethyl]piperazine
Reaction equation
[C:1]([C:3]([C:11]1[S:12][C:13]([C:16]#[N:17])=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6]I)#[N:2].[C:18]([C:20]1[N:25]=[C:24]([O:26][CH2:27][CH2:28][N:29]2[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]2)[CH:23]=[CH:22][CH:21]=1)#[N:19]>>[C:1]([C:3]([C:11]1[S:12][C:13]([C:16]#[N:17])=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6][N:32]1[CH2:33][CH2:34][N:29]([CH2:28][CH2:27][O:26][C:24]2[CH:23]=[CH:22][CH:21]=[C:20]([C:18]#[N:19])[N:25]=2)[CH2:30][CH2:31]1)#[N:2]Participants
3
Procedure
The title compound was synthesized in accordance with Example 75 from 4-cyano-4-(5-cyano-2-thienyl)-5-methylhexyl iodide and 1-[2-(6-cyano-2-pyridyloxy)ethyl]piperazine. The physico-chemical data of the compound was as below.
Sources & evidence
- ORD record
- ord-ec545599abc147ee9f80fc45f6fa1b81
- Source dataset
- uspto-grants-2005_06
- Patent number
- US06906072B1
Reaction notes
Loading…