HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 69747567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Trifluoroacetate | HCID 84468 | — |
| Reactant | HCID 11184883 | HCID 11184883 | — |
| Reactant | 5-methyl-N,N-dipropylisophthalamic acid | HCID 11391393 | — |
| Product | HCID 69747567 | HCID 69747567 | — |
Reaction Steps
The trifluoroacetate salt of (1S,2R,3R)-1-(3,5-difluorobenzyl)-2,3-dihydroxyheptylamine (0.1 mmol) was reacted with 3-methyl-5-[(dipropylamino)carbonyl]benzoic acid as described in method A (addition of an extra equivalent of DIEA to neutralize the amine salt) to give N1-[(1S,2R,3R)-1-(3,5-Difluorobenzyl)-2,3-dihydroxy-octyl]-5-methyl-N3,N3-dipropyl-isophthalamide. MS (ESI+) for C29H40F2N2O4 m/z 519 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06906104B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-3b1e1db239b6402db4501311c18ec90e |
| Source note | uspto-grants-2005_06 |