2-Methylbenzonitrile → beta-Dimethylamino-2-cyanostyrene

HRID 1071832Notes

Reaction equation

[CH3:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].C(O[CH:15](N(C)C)[N:16]([CH3:18])[CH3:17])(C)(C)C>>[CH3:15][N:16]([CH3:18])[CH:17]=[CH:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

Reactant 2

HCID 107212-Methylbenzonitrile

HCID 79885tert-Butoxy bis(dimethylamino)methane

Product 1

HCID 54125819beta-Dimethylamino-2-cyanostyrene

Procedure

Reaction of 2-methylbenzonitrile with 1-(t-butoxy)-N,N,N′,N′-tetramethylmethanediamine to give 2-(2-dimethylaminovinyl)benzonitrile has been reported (Fisher, U. et al. Helvetica Chimica Acta, 1990, 73, 763).

Sources & evidence

ORD record: ord-3981580fd0db47c1b58628d65166624a
Source dataset: uspto-grants-2005_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06906192B2

Reaction notes

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