HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1072009Generated: October 31, 2026
1-[[1-(2-Methylsulfanylethyl)benzimidazol-2-yl]methyl]benzotriazole → 1-[[1-(2-Methylsulfinylethyl)benzimidazol-2-yl]methyl]benzotriazole
https://huagongshe.com/reaction/1072009
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-[[1-(2-Methylsulfanylethyl)benzimidazol-2-yl]methyl]benzotriazole | HCID 5272015 | — |
| Reactant | Sodium;3-oxidodioxaborirane;tetrahydrate | HCID 23693097 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 1-[[1-(2-Methylsulfinylethyl)benzimidazol-2-yl]methyl]benzotriazole | HCID 5272016 | 80% |
Reaction Steps
1-[1-(2-Methylthio-ethyl)-1H-benzimidazol-2-ylmethyl]-1 H-benzotriazole (100 mg, 0.31 mmol) was dissolved in acetic acid (5 mL). Sodium perborate tetrahydrate (52 mg, 0.34 mmol) was added. The reaction mixture was stirred at 50° C. under nitrogen overnight. The acetic acid was evaporated under reduced pressure. Column chromatography (EtOAc, then EtOAc:MeOH=4:1) gave 84 mg (80%) of the title compound as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06908936B2 |
|---|
| Source dataset | uspto-grants-2005_06 |
|---|
| ORD ID | ord-0adec4e9dc8245aea73d06f7281c3a37 |
|---|
| Source note | uspto-grants-2005_06 |
|---|
