HCID 6481622, compound → HCID 5272002, compound

Participants

Reaction Steps

A mixture of 1-[1-(2-azido-ethyl)-1-H-benzimidazol-2-ylmethyl)-1H-benzotriazole (25 mg, 0.078 mmol) and 10% palladium on carbon in 1 mL of methanol was agitated under hydrogen at 55 psi for 5 hours. The reaction mixture was filtered through a pad of Celite and then through a Millipore membrane filter rinsing with methanol. The filtrate was stripped of solvent and dried under vacuum to give the amine (23 mg, quantitative yield) as a white solid.

Provenance & Evidence