HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4-fluoroaniline → 4-(3-Chloro-4-fluoro-phenylamino)-5-[3,5-dimethyl-4-(3-morpholin-4-YL-propyl)-1H-pyrrol-2-ylmethylene]-5,7-dihydro-pyrrolo[2,3-D]pyrimidin-6-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4-fluoroaniline | HCID 9708 | — |
| Reactant | 4-chloro-5-[3,5-dimethyl-4-(3-morpholin-4-yl-propyl)-1H-pyrrol-2-ylmethylene]-5,7-dihydro-pyrrolo [2,3-d]pyrimidin-6-one | HCID 85434170 | — |
| Product | 4-(3-Chloro-4-fluoro-phenylamino)-5-[3,5-dimethyl-4-(3-morpholin-4-YL-propyl)-1H-pyrrol-2-ylmethylene]-5,7-dihydro-pyrrolo[2,3-D]pyrimidin-6-one hydrochloride | HCID 70028555 | 10% |
Reaction Steps
The title compound (10% yield) was prepared from 4-chloro-5-[3,5-dimethyl-4-(3-morpholin-4-yl-propyl)-1H-pyrrol-2-ylmethylene]-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one and 3-chloro-4-fluoro-phenylamine according to the procedure described for Example 12.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06908930B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-e44c2a2d21694ce58bf7e4dd2f91dfb6 |
| Source note | uspto-grants-2005_06 |