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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1072249Generated: October 30, 2026

1-Phenethylamine, (+)- → ((1R)-1-Phenylethyl){[4-methoxy-3-(5-methoxy(3-pyridyl)) phenyl]methyl}amine

https://huagongshe.com/reaction/1072249

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Phenethylamine, (+)-HCID 643189—
Reactant4-Methoxy-3-(5-methoxypyridin-3-yl)benzaldehydeHCID 22391219—
Product((1R)-1-Phenylethyl){[4-methoxy-3-(5-methoxy(3-pyridyl)) phenyl]methyl}amineHCID 60010341—

Reaction Steps

The title compound (0.8 g, white solid as HCl salt) was prepared from 4-methoxy-3-(5-methoxy(3-pyridyl))benzaldehyde (0.71 g) and (R)-α-methylbenzylamine (0.371 mL) analogously to Example 66, step 3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06908935B2
Source datasetuspto-grants-2005_06
ORD IDord-003c698bf1a9493e8c8097a8dcc67c3d
Source noteuspto-grants-2005_06