7-[(Pyridin-3-yl)hydroxymethyl]imidazo[5,1-b]thiazole → 7-(Pyridin-3-yl)carbonylimidazo[5,1-b]thiazole

Participants

Reaction Steps

Manganese dioxide (1.0 g) was added to a solution of 1.02 g of 7-[(pyridin-3-yl)hydroxymethyl]imidazo[5,1-b]thiazole in 40 ml of dichloromethane, and the mixture was stirred at room temperature for 5 hr. The reaction solution was filtered through Celite, followed by washing with dichloromethane. The filtrate was concentrated under the reduced pressure to give 1.10 g of 7-(pyridin-3-yl)carbonylimidazo[5,1-b]thiazole.

Provenance & Evidence