6-Methyl-3-pyridinecarboxaldehyde → HCID 22390402, compound

HRID 1072333Notes

Reaction equation

HRID 1072333 reaction equation
I[C:2]1[N:3]=[CH:4][N:5]2[CH:9]=[CH:8][S:7][C:6]=12.[CH3:10][C:11]1[CH:16]=[CH:15][C:14]([CH:17]=[O:18])=[CH:13][N:12]=1>>[CH3:10][C:11]1[N:12]=[CH:13][C:14]([C:17]([C:2]2[N:3]=[CH:4][N:5]3[CH:9]=[CH:8][S:7][C:6]=23)=[O:18])=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 101925666-Methyl-3-pyridinecarboxaldehydeHCID 177737777-Iodoimidazo[5,1-B]thiazole

Product 1

HCID 22390402HCID 22390402, compoundYield 82.8%

Procedure

7-(6-Methylpyridin-3-yl)carbonylimidazo[5,1-b]-thiazole (885 mg) was prepared in the same manner as in step a) of Synthesis Example 3, except that 1.10 g of 7-iodoimidazo[5,1-b]thiazole and 532 mg of 2-methylpyridine-5-aldehyde were used as the starting compounds.

Workup

  1. customof Synthesis Example 3

Sources & evidence

ORD record
ord-c8e16e120f794be5ad4dd9e587e2ee51
Source dataset
uspto-grants-2005_06
Patent number
US06908913B2

Reaction notes

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