Tributyltin Chloride → HCID 22390227, compound

Participants

Reaction Steps

A ketone compound (327 mg) was prepared in substantially the same manner as in step b) of Synthesis Example 1, except that 577 mg of 7-[(quinolin-3-yl)hydroxymethyl]imidazo[5,1-b]thiazole and 421 mg of manganese dioxide were used as the starting compounds. 7-(Quinolin-3-yl)carbonyl-2-(tri-n-butylstannyl)imidazo-[5,1-b]thiazole (73 mg) was prepared in substantially the same manner as in step c) of Synthesis Example 1, except that 64 mg of the ketone compound, 0.140 ml of tri-n-butylstannyl chloride, and 1.50 ml of a 1.0 N lithium bis(trimethylsilyl)amide/THF solution were used as the starting materials.

Provenance & Evidence