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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1072344Generated: November 1, 2026

7-Iodoimidazo[5,1-B]thiazole → HCID 20802803, compound

https://huagongshe.com/reaction/1072344

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Iodoimidazo[5,1-B]thiazoleHCID 17773777—
ReactantHCID 20802795HCID 20802795—
ProductHCID 20802803HCID 2080280369.5%

Reaction Steps

7-[[(2S,4R)-4-t-Butyldimethylsilyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidin-2-yl]hydroxymethyl]-imidazo[5,1-b]thiazole (4.18 g) was prepared in the same manner as in step a) of Synthesis Example 1, except that 3.39 g of 7-iodoimidazo[5,1-b]thiazole and 4.61 g of (2S,4R)-4-t-butyldimethylsilyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine-2-aldehyde were used as the starting compounds.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06908913B2
Source datasetuspto-grants-2005_06
ORD IDord-5e80e1dc4e7e4df0b821a9e2c5a3e9bb
Source noteuspto-grants-2005_06