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HRID1072360

反应详情

EQUATION

反应方程式

HRID 1072360 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H](O)[C@H]1C(=O)N2[C@@H](C(=O)OCc3ccc([N+](=O)[O-])cc3)C(=O)[C@H](C)[C@H]12
HCID13504349

未命名化合物

结构：CCC[CH2][Sn]([CH2]CCC)([CH2]CCC)[c]1cn2cnc(C(=O)[C@@H]3CCCN3C(=O)OCc3ccc([N+](=O)[O-])cc3)c2s1
HCID69363645

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(c3cn4cnc(C(=O)[C@@H]5CCCN5C(=O)OCc5ccc([N+](=O)[O-])cc5)c4s3)[C@H](C)[C@H]12
HCID91103538

未命名化合物

收率 73.6%

PROCEDURE

实验过程

4-Nitrobenzyl (1S,5R,6S)-6-((1R)-1-hydroxyethyl)-1-methyl-2-[7-[(2S)-1-(4-nitrobenzyloxycarbonyl)-pyrrolidin-2-yl]carbonylimidazo[5,1-b]thiazol-2-yl]-1-carbapen-2-em-3-carboxylate (1.40 g) was prepared in the same manner as in step a) of Example 1, except that 926 mg of 4-nitrobenzyl (1R,3R,5R,6S)-6-((1R)-1-hydroxyethyl)-1-methyl-2-oxo-1-carbapenam-3-carboxylate and 1.85 g of 7-[(2S)-1-(4-nitrobenzyloxycarbonyl)-pyrrolidin-2-yl]carbonyl-2-(tri-n-butylstannyl)imidazo[5,1-b]thiazole were used as the starting compounds.