HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole → 3-(1H-Indol-3-yl)cyclopentanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole | HCID 798 | — |
| Reactant | 2-Cyclopenten-1-one | HCID 13588 | — |
| Reactant | 2,3-Dihydro-1,4-dioxino[2,3-f]-quinoline 2-methyltosylate | HCID 86594182 | — |
| Product | 3-(1H-Indol-3-yl)cyclopentanone | HCID 11344653 | 44% |
Reaction Steps
This compound was prepared in similar manner as for Intermediate 14, using indole (2.34 g, 20 mmol) and 2-cyclopenten-1-one (2.0 mL, 24.0 mmol) to give 1.7 g (44%) of the desired product as a thick oil: MS (ESI) m/z 200 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06911445B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-fca9e5eec5644e798319d02092bd952f |
| Source note | uspto-grants-2005_06 |