Benzylamine → N-Benzyl-3-(1H-indole-3-yl)-cyclopentylamine

Participants

Reaction Steps

This compound was prepared in similar manner as for Intermediate 17, using 3-(1H-indol-3-yl)-cyclopentanone (3.0 g, 15 mmol) and benzylamine (1.95 g, 18 mmol) to give 4.7 g of the desired product as a mixture of cis and trans isomers, which were separated by flash chromatography to afford 0.6 g of the cis isomer (first eluting) and 1.0 g of the trans isomer.

Provenance & Evidence