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HRID1072455

反应详情

EQUATION

反应方程式

HRID 1072455 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(S(=O)(=O)OCC2COc3ccc4nc(C)ccc4c3O2)cc1
HCID21892063

(8-Methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl)methyl 4-methylbenzene-1-sulfonate

C20H19NO5S

结构：N[C@H]1CC[C@@H](c2c[nH]c3ccc(F)cc32)CC1
HCID178511503

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc2c3c(ccc2n1)OC[C@H](CN[C@H]1CC[C@@H](c2c[nH]c4ccc(F)cc42)CC1)O3
HCID178422484

未命名化合物

收率 20.2%

PROCEDURE

实验过程

This compound was prepared in a manner similar to Example 1, using toluene-4-sulfonic acid 8-methyl-2,3-dihydro-[1,4]dioxino[2,3-f]quinolin-2-ylmethyl ester (0.5 g, 1.29 mmol) and cis-4-(5-fluoro-1H-indol-3-yl)-cyclohexylamine (0.4 g, 1.72 mmol) to give 0.116 g (20%) product as an oxalate salt: MS (ESI) m/z 446 [M+H]+.

WORKUP

后处理

  1. customThis compound was prepared in a manner similar to Example 1