HuagongsheHuagongshe Chemistry Print Report · For research reference only
(8-Methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl)methyl 4-methylbenzene-1-sulfonate → HCID 178422485, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (8-Methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl)methyl 4-methylbenzene-1-sulfonate | HCID 21892063 | — |
| Reactant | HCID 178511504 | HCID 178511504 | — |
| Product | HCID 178422485 | HCID 178422485 | 18% |
Reaction Steps
This compound was prepared in a manner similar to Example 1, using toluene-4-sulfonic acid 8-methyl-2,3-dihydro-[1,4]dioxino[2,3-f]quinolin-2-ylmethyl ester (0.5 g, 1.29 mmol) and trans-4-(5-fluoro-1H-indol-3-yl)-cyclohexylamine (0.4 g, 1.72 mmol) to give 0.09 g (18%) product as the fumarate salt: MS (ESI) m/z 446 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06911445B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-b760bbcd15b44d37975d6aa6bb1322b7 |
| Source note | uspto-grants-2005_06 |