反应详情

To a stirred solution of N-(2-Hydroxy-phenyl)-benzamide (0.81 g, 3.80 mmol), and cesium carbonate (1.61 g, 4.94 mmol) in acetonitrile was added epibromohydrin (0.63 ml, 7.60 mmol). After 4 hours the reaction mixture was partitioned between dichloromethane and water. After evaporation of the organic solvent the residue was crystallised from petroleum ether and diethyl ether yielding (0.741 g, 73%).

1. customAfter 4 hours the reaction mixture was partitioned between dichloromethane and water
2. customAfter evaporation of the organic solvent the residue
3. customwas crystallised from petroleum ether and diethyl ether yielding (0.741 g, 73%)