Methanesulfonyl chloride → HCID 22386874, compound

HRID 1072521Notes

Reaction equation

HRID 1072521 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[C:10]([Cl:12])[CH:11]=1)[CH2:8][N:7]([CH3:13])[CH2:6][CH:5]2[C:14]1[CH:15]=[C:16]([NH2:20])[CH:17]=[CH:18][CH:19]=1.[CH3:21][S:22](Cl)(=[O:24])=[O:23]>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[C:10]([Cl:12])[CH:11]=1)[CH2:8][N:7]([CH3:13])[CH2:6][CH:5]2[C:14]1[CH:15]=[C:16]([NH:20][S:22]([CH3:21])(=[O:24])=[O:23])[CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 98361943-(6,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)aniline

Product 1

HCID 22386874HCID 22386874, compound

Procedure

The process is analogous to the method described in example 82, starting from the compound of example 35 and methanesulfonyl chloride.

Sources & evidence

ORD record
ord-16277215574c4aa198717f9e0d64425c
Source dataset
uspto-grants-2005_06
Patent number
US06911453B2

Reaction notes

Loading…