HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2,4-dimethoxybenzaldehyde → 2,4-Dimethoxy-5-pyridin-3-yl-benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2,4-dimethoxybenzaldehyde | HCID 668346 | — |
| Reactant | 3-Pyridinylboronic acid | HCID 2734378 | — |
| Product | 2,4-Dimethoxy-5-pyridin-3-yl-benzaldehyde | HCID 21981113 | 68% |
Reaction Steps
Ex-104A: 2,4-Dimethoxy-5-pyridin-3-yl-benzaldehyde was prepared in a similar manner as described in Ex-3A from pyridine-3-boronic acid and 5-bromo-2,4-dimethoxybenzaldehyde, 68% yield. 1H-NMR (CDCl3) δ 10.33 (s, 1H), 8.71 (d, J=1 Hz, 1H), 8.51–8.53 (m, 1H), 7.81 (s, 1H), 7.74–7.78 (m, 1H), 7.27–7.31 (m, 1H), 6.52 (s, 1H), 3.99 (s, 3H), 3.91 (s, 3H). HMRS (EI) calcd. for C14H13NO3: 243.0895; found: 243.0888.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07094801B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-fd3f66696ce2493987252185d90a7bbb |
| Source note | uspto-grants-2006_08 |