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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1072660Generated: November 3, 2026

Sodium Carbonate → HCID 22388581, compound

https://huagongshe.com/reaction/1072660

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CarbonateHCID 10340—
Reactant2-Thiopheneboronic acidHCID 2733960—
ReactantHCID 9840705HCID 9840705—
CatalystHCID 178418476HCID 178418476—
Solvent1,2-DimethoxyethaneHCID 8071—
ProductHCID 22388581HCID 2238858188.6%

Reaction Steps

The title compound (145 mg, 54%, yellow foam) was prepared from [2-(4-bromophenoxy)propyl][(methylethyl)sulfonyl]amine (265 mg, 0.788 mmol, prepared in example 1), 2-thienylboronic acid (125 mg, 0.946 mmol), dichlorobis(triphenylphosphine)palladium(II) (22 mg, 0.031 mmol), 2 M sodium carbonate (285 mg in 1.35 mL water), and 1,2-dimethoxyethane (5.25 mL) in a manner analogous to the procedure described in Example 8.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06911476B2
Source datasetuspto-grants-2005_06
ORD IDord-75fecaf254414afcb9c35f8e1c8162d0
Source noteuspto-grants-2005_06