HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminophthalide → 4-Aminophthalimide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminophthalide | HCID 720669 | — |
| Reactant | 1,3-Dihydro-1-oxoisobenzofuran-5-carbonitrile | HCID 821218 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Product | 4-Aminophthalimide | HCID 72915 | — |
| Product | 5-Aminophthalide | HCID 720669 | — |
Reaction Steps
A method for the preparation of 5-cyanophthalide has previously been described in Bull. Soc. Sci. Bretagne, 1951, 26, 35 and in Levy and Stephen, J. Chem. Soc., 1931, 867. By this method 5-aminophthalide is converted to the corresponding 5-cyanophthalide by diazotation followed by reaction with CuCN. 5-Aminophthalide was obtained from 4-aminophthalimide by a two step reduction procedure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06911548B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-dd20adba05ca44fbab12231b84b1252d |
| Source note | uspto-grants-2005_06 |