Peracetic Acid → HCID 12993978, compound

Participants

Reaction Steps

Analogously to the procedure indicated in Example P1, 955 mg (7 mmol) of 3-methylene-bicyclo[2.2.2]octan-2-one is reacted with 1.64 g (8.4 mmol) of 32% peracetic acid in the presence of 286 mg (21 mmol) of sodium acetate trihydrate. 1 g of 4-methylene-3-oxa-bicyclo[3.2.2]nonan-2-one is isolated. After purification by column chromatography using 10% ethyl acetate in hexane, pure 4-methylene-3-oxabicyclo[3.2.2]nonan-2-one is obtained in the form of an oil.

Provenance & Evidence