HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1-(5-Bromo-1-benzofuran-2-yl)ethan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Bromoacetone | HCID 11715 | — |
| Reactant | 5-Bromosalicylaldehyde | HCID 72863 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | 1-(5-Bromo-1-benzofuran-2-yl)ethan-1-one | HCID 705670 | 87.8% |
Reaction Steps
5-Bromo salicylaldehyde (10.05 g), bromo acetone (8.0 g) and potassium carbonate (13.80 g) were refluxed for 1 hr in 2-butanone (100 ml). 2-Butanone (ca. 50 ml) was evaporated and ice was added. The precipitate was collected by filtration and washed with water and hexane to give the objective compound (10.50 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06911469B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-77f6a9a379cd467caaeb9aa6769a2fed |
| Source note | uspto-grants-2005_06 |