反应详情

4-Ethyl-3-nitrobenzoic acid (5.0 g, 27.4 mmol) was dissolved in methanol (50 ml) and a Pd-C catalyst (5%, 250 mg) was added thereto. The mixture was stirred under a hydrogen atmosphere from 0° C. to room temperature for 1 hr. After the completion of the reaction, the catalyst was filtered off and the filtrate was concentrated under reduced pressure. The obtained crystals were washed with methyl t-butyl ether/hexane and dried to give the object compound (3.2 g, 70.6%).

1. customAfter the completion of the reaction
2. filtrationthe catalyst was filtered off
3. concentrationthe filtrate was concentrated under reduced pressure
4. washThe obtained crystals were washed with methyl t-butyl ether/hexane
5. customdried