HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiazolidinedione → HCID 73885113, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiazolidinedione | HCID 5437 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | HCID 22388400 | HCID 22388400 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 73885113 | HCID 73885113 | 73.3% |
Reaction Steps
A suspension of methyl 3-(2-chloro-4-formylbenzyl)-2-methyl-3H-imidazo[4,5-b]pyridine-5-carboxylate (200 mg, 0.582 mmol), thiazolidine-2,4-dione (82 mg, 0.698 mmol) and piperidine (25 mg, 0.291 mmol) in ethanol (4 ml) was refluxed under heating overnight. The reaction mixture was cooled, and the precipitated crystals were filtrated to give the objective compound (189 mg) as pale-yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06911469B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-73ff4809face4256831c96616caa7b2f |
| Source note | uspto-grants-2005_06 |