Pyridine → 4-butyl-N-[[3-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-2-sulfanylidene-1H-imidazol-4-yl]methyl]benzamide

HRID 107291Notes

Reaction equation

HRID 107291 reaction equation
[CH2:21]([CH2:22][CH2:23][CH3:24])[c:25]1[cH:26][cH:27][c:28]([C:29](=[O:30])[Cl:31])[cH:32][cH:33]1.[NH2:1][CH2:2][c:3]1[cH:4][nH:5][c:6](=[S:20])[n:7]1[CH:8]1[CH2:9][c:10]2[cH:11][c:12]([F:19])[cH:13][c:14]([F:18])[c:15]2[CH2:16][CH2:17]1.[cH:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1>>[NH:1]([CH2:2][c:3]1[cH:4][nH:5][c:6](=[S:20])[n:7]1[CH:8]1[CH2:9][c:10]2[cH:11][c:12]([F:19])[cH:13][c:14]([F:18])[c:15]2[CH2:16][CH2:17]1)[C:29]([c:28]1[cH:27][cH:26][c:25]([CH2:21][CH2:22][CH2:23][CH3:24])[cH:33][cH:32]1)=[O:30]

Participants

4

Reactant 3

HCID 1049PyridineHCID 1200494-Butylbenzoyl chlorideHCID 63670795-(Aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1,3-dihydro-2H-imidazole-2-thione

Product 1

HCID 196993824-butyl-N-[[3-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-2-sulfanylidene-1H-imidazol-4-yl]methyl]benzamide

Sources & evidence

ORD record
ord-d56749880951470ab0ff263105bc5652
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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