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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 107292Generated: October 25, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(3-hydroxy-3-methylbut-1-yn-1-yl)pyridin-2-yl]amino}thiophene-3-carboxamide

https://huagongshe.com/reaction/107292

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Reactant4-(6-Bromopyridin-2-yl)-2-methylbut-3-yn-2-olHCID 59525879—
Product5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(3-hydroxy-3-methylbut-1-yn-1-yl)pyridin-2-yl]amino}thiophene-3-carboxamideHCID 59526135—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-dd01f64954c5418ab6c4d88a496c9e52
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)