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HRID1072939

反应详情

EQUATION

反应方程式

HRID 1072939 的结构方程式

REACTANTS

反应物

1
结构：COC(=O)[C@H](O)[C@@H](N=[N+]=[N-])c1ccccc1
HCID10059351

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@H](O)[C@@H](N)c1ccccc1
HCID10176516

(2R,3S)-3-Phenylisoserine methyl ester

C10H13NO3

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

The (2R,3S)-3-azido-2-hydroxy-3-phenylpropionic acid methyl ester (1, 0.5 g) is hydrogenated over 10% palladium on carbon (0.1 g) in ethanol at atmospheric pressure for 1 hour. The reaction is filtered and evaporated to yield the desired amine. Mp 106-108° C.

WORKUP

后处理

  1. filtrationThe reaction is filtered
  2. customevaporated