Sodium Hydroxide → 1-Oleoyl-lyso-phosphatidic acid

Participants

Reaction Steps

6 (1 mmol) is dissolved in 10 ml of dichloromethane, and 25 ml of a 1% methanolic NaOH solution is added. This is concentrated after 20 hours at room temperature, and the residue is acidified with 1N HCl. The mixture is extracted with ethyl acetate. The combined organic phases are washed with 20 ml of H2O and dried over MgSO4, filtrated and concentrated. The residue is treated with methanol. Yield: 78% of colorless crystals.

Provenance & Evidence