Ethanol → HCID 22158084, compound

Participants

Reaction Steps

A mixture of ethanol (3.9 g), water (0.2 g), conc.sulphuric acid (3.9 g) and 3-propyloxyphenylacetonitrile (3.5 g; 20 mmol) was heated under reflux during 6 hours. After cooling, ether (20 ml) and water (20 ml) were added and the mixture was stirred. The phases were separated and the ethereal extract washed with 10% potassium bicarbonate (2×20 ml), dried over Na2SO4, filtered and evaporated to dryness to give a pale tan oil.

Provenance & Evidence