6-(Benzyloxy)-7-(5-(4-fluorobenzyl)thiazol-2-yl)-1-(2-oxo-2-(piperazin-1-yl)ethyl)imidazo[1,2-a]pyrimidin-5(1H)-one → 7-[5-[(4-Fluorophenyl)methyl]-1,3-thiazol-2-yl]-6-hydroxy-1-(2-oxo-2-piperazin-1-ylethyl)imidazo[1,2-a]pyrimidin-5-one
Reaction equation
[CH2:19]([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[O:26][c:27]1[c:28](-[c:46]2[s:47][c:48]([CH2:51][c:52]3[cH:53][cH:54][c:55]([F:58])[cH:56][cH:57]3)[cH:49][n:50]2)[n:29][c:30]2[n:31]([c:32]1=[O:33])[cH:34][cH:35][n:36]2[CH2:37][C:38]([N:39]1[CH2:40][CH2:41][NH:42][CH2:43][CH2:44]1)=[O:45].[CH3:1][O:2][C:3]([c:4]1[n:5][c:6]2[nH:7][cH:8][cH:9][n:10]2[c:11](=[O:12])[c:13]1[O:14][C:15](=[O:16])[CH3:17])=[O:18]>>[OH:26][c:27]1[c:28](-[c:46]2[s:47][c:48]([CH2:51][c:52]3[cH:53][cH:54][c:55]([F:58])[cH:56][cH:57]3)[cH:49][n:50]2)[n:29][c:30]2[n:31]([c:32]1=[O:33])[cH:34][cH:35][n:36]2[CH2:37][C:38]([N:39]1[CH2:40][CH2:41][NH:42][CH2:43][CH2:44]1)=[O:45]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5f7dc8b518aa492da6242b548855ab72
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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