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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1073273Generated: October 25, 2026

Water → 3-Amino-2-(4-chlorophenyl)-4-quinolinecarboxylic acid

https://huagongshe.com/reaction/1073273

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantIsatinHCID 7054—
Reactant2-Amino-1-(4-chlorophenyl)ethan-1-one hydrochlorideHCID 2798211—
Product3-Amino-2-(4-chlorophenyl)-4-quinolinecarboxylic acidHCID 15085970—

Reaction Steps

A solution of 5.8 g of isatin in water was reacted with 12.0 g of 2-amino-1-(4-chlorophenyl)ethanone hydrochloride by the procedure described in example 33, giving 8.1 g of the desired compound as a yellow solid, mp 243°-244° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04968702
Source datasetuspto-grants-1990_11
ORD IDord-6fbb4555491d463d9552b2af142c8680
Source noteuspto-grants-1990_11