HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Amino-6,8-dichloro-2-(4-chlorophenyl)-4-quinolinecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 5,7-Dichloro-1H-indole-2,3-dione | HCID 80771 | — |
| Reactant | 2-Amino-1-(4-chlorophenyl)ethan-1-one hydrochloride | HCID 2798211 | — |
| Product | 3-Amino-6,8-dichloro-2-(4-chlorophenyl)-4-quinolinecarboxylic acid | HCID 15085971 | — |
Reaction Steps
A solution of 5.4 g of 5,7-dichloroisatin in water was reacted with 7.21 g of 2-amino-1-(4-chlorophenyl)ethanone hydrochloride by the procedure described in example 33, giving 5.2 g of the desired compound as a yellow solid, mp 260°-261° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04968702 |
| Source dataset | uspto-grants-1990_11 |
| ORD ID | ord-d3c17c6d13534627a14b7bd5ede15e74 |
| Source note | uspto-grants-1990_11 |