Water → HCID 15085976, compound

HRID 1073279Notes

Reaction equation

HRID 1073279 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=O.Cl.[NH2:14][CH2:15][C:16]([C:18]1[CH:23]=[CH:22][C:21]([I:24])=[CH:20][CH:19]=1)=O.[OH2:25]>>[NH2:14][C:15]1[C:16]([C:18]2[CH:23]=[CH:22][C:21]([I:24])=[CH:20][CH:19]=2)=[N:7][C:8]2[C:4]([C:5]=1[C:6]([OH:11])=[O:25])=[CH:3][C:2]([F:1])=[CH:10][CH:9]=2

Participants

4

Reactant 3

HCID 962WaterHCID 2365665-FluoroisatinHCID 221583482-Amino-1-(4-iodophenyl)ethan-1-one--hydrogen chloride (1/1)

Product 1

HCID 15085976HCID 15085976, compound

Procedure

A basic aqueous solution of 3.8 g of 5-fluoroisatin in water was reacted with 9.8 g of 2-amino-1-(4-iodophenyl)ethanone hydrochloride by the procedure described in example 41, giving 7.0 g of the desiredcompound as a yellow solid, mp 251°-253° C.

Workup

  1. customgiving 7.0 g of the desiredcompound as a yellow solid, mp 251°-253° C.

Sources & evidence

ORD record
ord-371c011deb5a43e2935ce14d367639db
Source dataset
uspto-grants-1990_11
Patent number
US04968702

Reaction notes

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