反应详情

Then, 2.38 g (19.0 mmol) of thionyl chloride was maintained at a temperature of 36°~38° C. in a flask, to which was added dropwise 2.51 g (15.9 mmol) of the above (+)-2-methyl octanoic acid over 7 minutes with stirring. After the reaction with stirring at room temperature for 40 minutes, the reaction was further continued by stirring at a temperature of 80° C. for 30 minutes. Then, the reaction product was distilled to obtain 2.81 g (15.9 mmol, yield: 100%) of a colorless and transparent (+)-2-methyl octanoyl chloride.

1. customAfter the reaction
2. stirringwith stirring at room temperature for 40 minutes
3. stirringby stirring at a temperature of 80° C. for 30 minutes
4. distillationThen, the reaction product was distilled