Thiophosgene → HCID 19891711, compound

HRID 1073476Notes

Reaction equation

HRID 1073476 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])=[CH:10][N:9]=2)=[CH:4][CH:3]=1.[C:19](Cl)(Cl)=[S:20]>>[N:1]([C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:9]=[CH:10][C:11]([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])=[CH:12][N:13]=2)=[CH:6][CH:7]=1)=[C:19]=[S:20]

Participants

3

Reactant 2

HCID 10040ThiophosgeneHCID 22157292HCID 22157292, compound

Product 1

HCID 19891711HCID 19891711, compound

Procedure

2-(4-Aminophenyl)-5-pentylpyrimidine (prepared from 4-aminophenylamidine and 2-pentylpropane-1,3-diol) is reacted with thiophosgene as described in Example 3, affording 2-(4-isothiocyanatophenyl)-5-pentylpyrimidine; m.p. 46°, c.p. 85.5°.

Sources & evidence

ORD record
ord-5fd09cb9cf744ed08895ccfa77489a58
Source dataset
uspto-grants-1990_11
Patent number
US04970022

Reaction notes

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