Enclomiphene → Clomiphene

HRID 1073582Notes

Reaction equation

[CH3:1][CH2:2][N:3]([CH2:6][CH2:7][O:8][C:9]1[CH:10]=[CH:11][C:12](/[C:15](/[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)=[C:16](/[Cl:23])\[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[CH:13][CH:14]=1)[CH2:4][CH3:5].CCN(CCOC1C=CC(/C(/C2C=CC=CC=2)=C(/Cl)\C2C=CC=CC=2)=CC=1)CC.C(C(O)(C(O)=O)CC(O)=O)C(O)=O>>[CH2:4]([N:3]([CH2:2][CH3:1])[CH2:6][CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]([C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)=[C:16]([Cl:23])[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:11][CH:10]=1)[CH3:5]

Participants

Reactant 2

HCID 1548953Enclomiphene

HCID 6420009Enclomiphene citrate

Product 1

HCID 2800Clomiphene

Procedure

clomifene; chloramiphene; C26H28ClNO; mol. wt. 405.98, is as follows: ##STR1##

Sources & evidence

ORD record: ord-37899962c7bf406e99ef226b3c253166
Source dataset: uspto-grants-1990_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04970237

Reaction notes

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