HCID 67913331, compound → HCID 86744341, compound

HRID 1073685Notes

Reaction equation

HRID 1073685 reaction equation
[ClH:1].NCCSC1SC=C(C(NC2S[C:16]3[CH:22]=[CH:21][C:20](F)=[CH:19][C:17]=3C=2)=O)N=1.Cl.[NH2:25][CH2:26][CH2:27][S:28][C:29]1[S:30][CH:31]=[C:32]([C:34]([NH:36][CH:37]2[N:41](C)[C:40]3[CH:43]=[C:44](F)[CH:45]=[CH:46][C:39]=3[S:38]2)=[O:35])[N:33]=1>>[ClH:1].[NH2:25][CH2:26][CH2:27][S:28][C:29]1[S:30][CH:31]=[C:32]([C:34]([NH:36][C:37]2[S:38][C:39]3[CH:46]=[C:45]([C:16]4[CH:22]=[CH:21][CH:20]=[CH:19][CH:17]=4)[CH:44]=[CH:43][C:40]=3[N:41]=2)=[O:35])[N:33]=1

Participants

3

Reactant 2

HCID 67913331HCID 67913331, compoundHCID 67913336HCID 67913336, compound

Product 1

HCID 86744341HCID 86744341, compound

Procedure

In a similar manner were prepared: 2-(aminoethylthio)-N-(5-fluorobenzothiol-2-yl) thiazole-4-carboxamide hydrochloride, m.p. 261-263° C. dec. and 2-(aminoethylthio)-N-(3-methyl-5-fluorobenzothiazol-2-yl)thiazole-4-carboxamide hydrochloride, m.p. 276-277° C. dec.

Workup

  1. customIn a similar manner were prepared

Sources & evidence

ORD record
ord-0e820138bb3c4cd8801c6f8dda999609
Source dataset
uspto-grants-1990_11
Patent number
US04970318

Reaction notes

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