Water → HCID 13037828, compound

HRID 1073700Notes

Reaction equation

HRID 1073700 reaction equation
[CH2:1]([CH:7](O)[C:8]1[O:12][CH:11]=[CH:10][CH:9]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[OH2:14]>>[CH2:1]([CH:7]1[CH:8]([OH:12])[CH:9]=[CH:10][C:11]1=[O:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

3

Reactant 2

HCID 962WaterHCID 10511647HCID 10511647, compound

Product 1

HCID 13037828HCID 13037828, compoundYield 65%

Procedure

In the same apparatus as in Example 1, α-n-hexylfurfuryl alcohol (30 parts) and water (1500 parts) were charged, and the resultant mixture was stirred at 100° C., during which the pH was maintained at 4.6 to 5.0 until the starting compound was consumed. The reaction mixture was treated as in Example 1, followed by purification with chromatography to give 2-n-hexyl-3-hydroxy-4-cyclopentenone in a yield of 65 %.

Workup

  1. temperaturewas maintained at 4.6 to 5.0 until the starting compound
  2. customwas consumed
  3. additionThe reaction mixture was treated as in Example 1
  4. customfollowed by purification with chromatography

Sources & evidence

ORD record
ord-316b82ae5d814d2cbb7d4a70f05e27a4
Source dataset
uspto-grants-1990_11
Patent number
US04970345

Reaction notes

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