HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 14858903, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Hexane | HCID 8058 | — |
| Reactant | HCID 14858901 | HCID 14858901 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 14858903 | HCID 14858903 | 98.4% |
Reaction Steps
N-t-butyloxycarbonyl-L-seryl-L-proline benzylester (33.99 g, 86.6 mmole) was dissolved in 4N hydrochloric acid in dioxane (300 ml) solution, and stirred for 1 hour at room temperature. To the solution, diethyl ether (500 ml) and n-hexane (100ml) were added to give L-seryl-L-proline benzylester hydrochloride (yield: 28.03 g, 98.4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04971993 |
| Source dataset | uspto-grants-1990_11 |
| ORD ID | ord-d0443245c29e44a28eef45080313bca2 |
| Source note | uspto-grants-1990_11 |