Sodium Hydroxide → HCID 86743591, compound

HRID 1074068Notes

Reaction equation

HRID 1074068 reaction equation
[OH:1][C:2](=[CH:8][CH:9]=[C:10]([S:16][C:17]1[CH:26]=[CH:25][C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:18]=1)[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C:3]([O:5]CC)=[O:4].[OH-].[Na+]>C(O)C>[OH:1][C:2](=[CH:8][CH:9]=[C:10]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[S:16][C:17]1[CH:26]=[CH:25][C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:18]=1)[C:3]([OH:5])=[O:4]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86743592HCID 86743592, compound

Product 1

HCID 86743591HCID 86743591, compoundYield 81.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

The procedure is as in Example 39, starting with diethyl 2-hydroxy-5-(2-naphthylthio)-2,4-hexadienedioate, (2 g), 1N aqueous sodium hydroxide solution (80 cc) and ethanol (100 cc). 2-Hydroxy-5-ethoxycarbonyl-5-(2-naphthylthio)-2,4-pentadienoic acid (1.5 g), m.p. 182° C., is obtained by precipitation in ethanol.

Sources & evidence

ORD record
ord-259becc68f074fc6b2d2de2d48bb842a
Source dataset
uspto-grants-1990_11
Patent number
US04971979

Reaction notes

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