HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenyl-1,2-propanedione → 4-Dimethylamino-1-phenyl-3-butene-1,2-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenyl-1,2-propanedione | HCID 11363 | — |
| Reactant | Dimethylformamide diethylacetal | HCID 70913 | — |
| Reactant | Ethyl 4-(dimethylamino)-2-oxo-but-3-enoate | HCID 2777802 | — |
| Product | 4-Dimethylamino-1-phenyl-3-butene-1,2-dione | HCID 54572896 | — |
Reaction Steps
The procedure is as in Example 2 for the preparation of ethyl 4-dimethylamino-2-oxo-3-butenoate, starting with 1-phenyl-1,2-propanedione (25 g) and N,N-dimethylformamide diethyl acetal (28.3 g). After purification by chromatography on a silica column with ethyl acetate as eluent, 4-dimethylamino-1-phenyl-3-butene-1,2-dione (9.3 g), m.p. 88° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04971979 |
| Source dataset | uspto-grants-1990_11 |
| ORD ID | ord-fca36f9a351749c48cfadbd24d451ccf |
| Source note | uspto-grants-1990_11 |