HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Thioglycolate → Ethyl (2,4,6-trimethylbenzylthio)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Thioglycolate | HCID 12185 | — |
| Reactant | 2,4,6-Trimethylbenzyl chloride | HCID 74108 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | Ethyl (4-methylbenzylthio)acetate | HCID 4107274 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl (2,4,6-trimethylbenzylthio)acetate | HCID 13245053 | — |
Reaction Steps
The procedure is as in Example 29 for the preparation of ethyl (4-methylbenzylthio)acetate, starting with 2,4,6-trimethylbenzyl chloride (10.25 g), a 2M ethanolic solution of sodium ethylate (32.5 cc) and ethyl 2-mercaptoacetate (7.1 g) in ethanol (150 cc). Ethyl (2,4,6-trimethylbenzylthio)acetate (11 g) is thereby obtained, and is used in the crude state in the subsequent syntheses.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04971979 |
| Source dataset | uspto-grants-1990_11 |
| ORD ID | ord-982536e5629c4561a114a12a1c47c86c |
| Source note | uspto-grants-1990_11 |