HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenacyl bromide → (2-Oxo-2-phenylethyl)(triphenyl)phosphanium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenacyl bromide | HCID 6259 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | (2-Oxo-2-phenylethyl)(triphenyl)phosphanium bromide | HCID 197064 | 93.3% |
Reaction Steps
50.0 g. (251mmoles) of α-bromoacetophenone (Compound CI) and 65.9 g. (251 mmoles) of triphenylphosphine are stirred in 500 ml. of toluene at 20°-25° C. under nitrogen for 16 hours, and the resulting solid is collected by filtration, rinsed with toluene and rinsed with diethyl ether to obtain the product as a white powder (107.98 g. (93%)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04973704 |
| Source dataset | uspto-grants-1990_11 |
| ORD ID | ord-326ceb0eb86c41169175edd1c1c7e54f |
| Source note | uspto-grants-1990_11 |